The science behind what we leave out.

Sorrel & Co is defined as much by what we exclude as what we include. This page documents the peer-reviewed clinical evidence behind every “free from” claim we make — and flags, honestly, the formulas that contain an exception.

17Formulas, all manufactured in the US
7Ingredient categories researched
30+Peer-reviewed studies cited

Why this exists

Most skincare brands make ingredient claims. Few cite the evidence behind them.

We built Sorrel & Co because the gap between what skincare formulations contain and what most people actually understand about those ingredients is enormous. Walk into any beauty aisle and you’ll see hundreds of products labeled “clean,” “natural,” or “free from” — terms that mean almost nothing under US labeling law. The FDA does not regulate the term “clean.” Manufacturers can call almost anything natural.

So instead of marketing claims, we publish citations. When we exclude an ingredient, we do it for documented reasons — and when a formula still contains one, we flag it in the table below rather than round up to a claim that isn’t true. We use PubMed links so you can verify everything yourself.

The seven ingredient categories below cover the most consequential exclusions. We’ve graded each one by evidence strength — because not every “free from” claim is equally supported, and pretending otherwise would betray the trust of the customers we want most: the ones who read labels.

Connor

The science is either there or it isn’t. Here we show you which, and how strong the evidence is. — CONNOR

What our formulas are free from — and the exceptions

All 17 formulas are USA-made. Most are free from synthetic fragrance, parabens, silicones, and drying alcohol — but not every one, and we flag each exception in the table rather than round up. Most are vegan and cruelty-free; those exceptions are marked too.

ProductKey IngredientSynthetic Fragrance-FreeParaben-FreeVeganCruelty-FreeSilicone-FreeAlcohol-Free
Face SerumRetinol & Liposomes
Hydration Serum4-Weight Hyaluronic Acid
Glow SerumVitamins B3, C & E
Clarity Serum10% Niacinamide
Defense SerumGreen Tea EGCG
Repair SerumSnail Mucin & Centella**
Firming CreamDMAE & CoQ10§
Dew CreamNiacinamide & Allantoinb
Renewal CreamRetinol & Ceramides
Eye CreamAcetyl Tetrapeptide-5
Face OilJojoba, Squalane & Magnoliab
Balance GelGreen Tea & Bisabololb
Daily CleanserLicorice & Mushroom
Clearing CleanserTea Tree & Charcoalb
Brightening BarKojic Acid & Turmericb
Calming MistRose Water & Aloeb
Collagen PowderHydrolyzed Bovine Collagen**

* Repair Serum contains snail secretion (animal-derived) — not vegan — and cosmetic silicones (dimethicone). Cruelty-free per industry definition.
** Collagen Powder is bovine-derived — not vegan or vegetarian. Cruelty-free per industry definition.
† Renewal Cream contains added fragrance and milk lipids (dairy) — not synthetic-fragrance-free or vegan.
‡ Balance Gel and Daily Cleanser each contain a small amount of denatured or ethyl alcohol — not alcohol-free.
§ Firming Cream’s preservative system (Phenonip) contains parabens — not paraben-free.
b Free from synthetic fragrance, but contains a naturally derived botanical or essential oil, or a floral water (Balance Gel, Brightening Bar, Calming Mist, Clearing Cleanser, Dew Cream, Face Oil).

7 ingredient categories we scrutinize — and the research behind why

We keep these out of our formulas wherever the formula allows. A few products still contain a small amount of one — denatured alcohol, silicones, or a paraben-based preservative — and every one is flagged in the table above. Here is the research on why we minimize them.

Not all “free from” claims are equally supported

The evidence for excluding different ingredients varies in strength. Being upfront about that hierarchy is itself a differentiator. We grade our exclusions in three tiers.

Strongest

Fragrance, sulfates, phthalates. Multiple well-designed studies, consistent findings, clear mechanisms, decades of clinical data.

Strong

Parabens, denatured alcohol. Real effects established; the most-cited concern is qualified (paraben causation not proven; alcohol effect is concentration-dependent). Regulatory action or clinical caution supports precaution.

Mixed

Silicones, mineral oil. The case is real but qualified — environmental more than dermatological for silicones, functional rather than safety for mineral oil. We tell you which.

A brand that tells you the evidence against silicones is mostly environmental rather than dermatological is more credible than one that treats every “free from” claim as equally backed by science. We choose precision over marketing language because the customer who reads labels respects it.

How we evaluate research

Every claim on this page is supported by peer-reviewed research published in dermatology, toxicology, or environmental health journals. We rely primarily on:

  • Multicenter clinical studies — large patch test datasets like NACDG and EU registries
  • Mechanistic research — studies showing how an ingredient affects skin biology
  • Regulatory positions — EU restrictions and EWG ratings as supporting context, not primary evidence
  • Peer-reviewed reviews for synthesis

We do not cite:

  • Single-source blog posts or aggregated “natural beauty” databases
  • Industry-funded studies without independent corroboration
  • Animal-only studies as standalone evidence for human relevance

We update this page as new research emerges. Last reviewed: July 2026.

Latest from our research blog

Long-form writing on ingredients, formulation, and how to use what you put on your face.